EPIZYME is used as one component in the treatment of Exocrine Pancreatic Insufficiency (EPI) in dogs and cats. EPI is a condition where the pancreas does not manufacture enough of the digestive enzymes necessary for the animal to properly digest and absorb the required nutrients from their food. This condition must be managed for the duration of the animal’s life. Without daily treatment the disease is fatal as the animal will slowly die of malnutrition. Pancreatin is considered a critical care component of any EPI treatment protocol.